Ever thought of the internal factors responsible for the stress response of your body system to some situations around you? The reasons can be different, the way your system responds to stress or how well your system relaxes after experiencing severe stress.

Cortisol is the major hormone responsible for this. It is known as the stress hormone, some even call it the body’s alarm system. It is in charge of your system’s biological reaction to specific stimuli in your immediate surroundings. It could indicate exhaustion or a warning against threats whether to the mind or the body. Cortisol is also responsible for the flight or fight reflexes you experience when you find yourself in dangerous situations. Some of its other responsibilities include:

  1. Regulating carbohydrates, proteins, and fats level in the body
  2. Keeping inflammation in check
  3. Managing blood pressure
  4. Ruling your sleep cycle
  5. Boosting blood sugar

More cortisol means more energy to negate stress, which ends up being regulated. It means that cortisol is essential to an active human being. When it is in excess, you stand the risk of becoming overweight and that weakens your muscles. It also makes your skin more fragile and prone to bruises, and the chances of you having diabetes skyrockets. When you are short on cortisol, you get weak easily, you become prone to fatigue and your blood pressure drops immensely. When you are short on cortisol, you become predisposed to Addison’s disease. Considering that the disease is a condition that indicates that your adrenal glands aren’t secreting enough cortisol. You may begin to wonder what exactly is the correlation between this and cannabis? Well, it’s straightforward, cannabis and these stress hormones interact.

Cannabis and stress: the relationship between stress hormones and marijuanaHow do stress hormones and cannabis interact?

The endocannabinoid system (ECS) and the cannabinoid receptors in the human body are the channels with which cannabis and the stress hormones use for interactions.

The endocannabinoid system (ECS) has a significant influence over many activities in the human system, some of which include digestion, mood, stress, sleep, appetite, memory, and even muscle development. From research, it has been proven that the THC reacts well with the hypothalamus pituitary adrenal (HPA) axis, which is in charge of the stress hormones. This axis judges your body’s response to stress via the secretion of cortisol by the adrenal glands.

When the elimination of stressors has taken root, the residual cortisol contacts the hypothalamus and pituitary gland to halt the process that leads to the secretion of cortisol. As much as elevated levels of cortisol are normal, maintaining these elevated levels for a lengthy period can cause a negative impact. Now, this is where cannabis comes in, the work cannabis does is to elevate the level of cortisol in the body.

For occasional users of cannabis, the rise in cortisol levels tends to yield anxiety and a rise in blood pressure with time. For frequent users, exposure to marijuana can lead to a dampening response to stress. It means the body ceases to respond effectively to cortisol and its stress-judging activities.

From the study, researchers have been able to explain that habitual marijuana users show no rise in cortisol level when faced with situations that can cause stress. This indicates that their stress response was in the red zone something close to zero. On the surface, it may look like a good thing considering it means they can challenge stressful situations and are more resistant to stress. Don’t be fooled that’s just one half of the case, the other half indicates that, their low-stress response leads to poor awareness of threat or danger. Carrie Cuttler, neuroscience and integrative psychology assistant professor reported that this inability to recognize danger via hormonal distress is generally harmful to the individual. Consider the flight or fight reflexes, if these reflexes are dampened your body will lose the ability to warn you of imminent danger, putting your life at risk by doing that.

Are we saying that cannabis doesn’t relieve stress? This is an important question, considering that tons of reliable sources have confirmed that ingesting cannabis can help you relax and relieve you of stress. With all the negative impacts of cannabis ingestion already discussed, can any benefit be derived from cannabis?

Luckily, there are. A study by researchers at the University of Chicago aimed to prove if cannabis can truly relieve stress or maybe certain conditions must be met before this can happen. Their research evaluated the effect of 7.5 mg and 12.5 mg of THC on two distinct groups out of a total of 42 participants. A third group was assigned as the control group.  The necessary THC dose was administered to the first two groups. A mock interview was conducted to subject them to different stress circumstances. Before, during, and after these interviews, their stress levels were observed. The researchers paid attention to parameters such as cortisol levels, heart rate, and blood

Cannabis and stress: the relationship between stress hormones and marijuanapressure. The group with the least dosage of THC (7.5 milligrams) felt less stress during psychosocial activities when compared with those given 12.5 mg of THC. The second group with 12.5 milligrams showed increased stress levels, and anxiety levels were also amplified in the course of the test and after. Interestingly, heartbeat rate and cortisol levels did not experience any significant changes in the course of the test, after the test, and even before the test. All the groups had a similar experience in these parameters. They concluded that incredibly low doses of cannabis are capable of relieving stress. Increased stress and anxiety levels were observed in users who consumed higher doses of cannabis. Thus, cannabis can relieve stress levels and help you feel relaxed, but that’s only true for microdoses, higher doses do the exact opposite.


Adequate attention must be paid to the cortisol levels to ensure that it remains balanced in the body. Indiscriminate use of cannabis should be avoided to reduce the elevation of stress hormones or a significant decrease in its functions. Self-medicating on cannabinoids and THC are not advisable and thus you should consider professional opinion before attempting to use cannabis. If this option is not available at the store you buy cannabis, you should consider changing vendors. Buy cannabis Canada is a great option for you in this case. Aside from offering quality cannabis at affordable prices, we also provide expert opinions for new and experienced users on the healthiest does and amount of cannabis that is good for them. Our customer care service will answer any question you have about cannabis. You can take advantage of our ongoing promo to enjoy a 20% discount on any product you buy on our website. Make use of Canada20 as your promo code on the website.

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